BDBM50193145 2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acid::CHEMBL426560::Isoquinoline 3::N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE

SMILES OC(=O)CNC(=O)c1nc(Cl)c2ccccc2c1O

InChI Key InChIKey=OUQVKRKGTAUJQA-UHFFFAOYSA-N

Data  1 KI  25 IC50  3 Kd  1 EC50

PDB links: 19 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193145   

TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)Copy SMILESCopy InChI

Affinity DataIC50:  5.50E+5nMpH: 7.5Assay Description:Inhibition assays were carried out in 384-well white ProxiPlates(PerkinElmer) in 10 μL of reaction volume. Standard reaction mixturesconsisted o...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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